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� Abstract
� Introduction to contain information about the pathogen, the diseases caused, and clinical and economic significance
� Differentiating diagnostic characteristics [physiological and biochemical]
� Epidemiology including global incidence and effect on public health
� Mechanisms of pathogenesis and description of all the virulence antigens in detail including the damage causes to the host
� Evolution of vaccines: should include currently used vaccines, if there are any, and their advantages and disadvantages.
� Experimental vaccines under development, their disadvantages and advantages
� Currently used therapeutic strategies including treatment options currently adopted, their advantages and disadvantages
� Conclusions and future directions.
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