A Histidine titration curve that has a pKac= 1.8, pKan=6.0 and pKar=9.3. Draw the structure of histidine at each of the four stages of ionization. Identify the points on the graph that correspond to the four ionic species. Identify the points at which the averagenet charge is +2, +1, 0, -1. Identify the point that indicates complete titration of the side chain. At what pH ranges would histidine be a good buffer?
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