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Due to aging and alterations of disease, the cellular structure of the body changes across the lifespan. As a result, body systems begin to function differently and may react to drugs differently through pharmacokinetic and pharmacodynamic processes. In geriatric patients, the body absorbs, distributes, metabolizes, and excretes drugs differently than younger adults. Since the dosing guidelines for most drugs are not written to account for these differences, the potential for adverse reactions in geriatric patients increases. When prescribing drugs to geriatric patients, advanced practice nurses have to weigh benefits against potential harmful effects.
To prepare:
Review the Hilmer et al. article in the Learning Resources.
Select three drugs that you, as an advanced practice nurse, might prescribe to geriatric patients for cardiovascular and endocrine disorders.
Consider how changes in the pharmacokinetic and pharmacodynamic processes of geriatric patients might impact the effects of these drugs.
Consider the harm versus benefits ratio of treatment with these drugs.
Write a brief description of three drugs that you might prescribe to geriatric patients for cardiovascular and endocrine disorders.
Then, explain how changes in the pharmacokinetic and pharmacodynamic processes of geriatric patients might impact the effects of these drugs.
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