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1. Randomization and Estimation Constructs. Please choose one of the estimation constructs and one of the randomization constructs below. Then, identify a peer-reviewed journal article that highlights the construct. Compose a post in which you summarize and evaluate the constructs used in the research study.
Randomization constructs:
a. Random-number tables
b. Block randomization
c. Stratification
d. Random assignment
e. Pseudorandom numbers
Estimation constructs:
a. Point Estimation
b. Central Limit Theorem
c. Interval Estimation
d. t-distribution
e. Chi-square distribution
f. Maximum-likelihood distribution
Please review your classmates’ posts before submitting. Try to identify an estimation/randomization construct that was not already used (or was least used) in the discussion forum. Respond to at least two of your classmates’ postings.
2. Randomized Clinical Trials. This week, you learned about randomized clinical trials. Choose a phase of the clinical trial and explain the randomization and/or estimation implications for the phase. Please provide a current and relevant example of a specific clinical trial in your response. Clinical trial phases:
a. Phase I Trials
b. Phase II Trials
c. Phase III Trials
d. Phase IV Trials
e. Respond to at least two of your classmates’ postings.
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